LRRK2 pathobiology in Parkinson's disease
نویسندگان
چکیده
منابع مشابه
LRRK2 and Parkinson disease.
OBJECTIVES To review the molecular genetics and functional biology of leucine-rich repeat kinase 2 (LRRK2) in parkinsonism and to summarize the opportunities and challenges to develop interventions for Parkinson disease (PD) based on this genetic insight. DATA SOURCES Publications cited are focused on LRRK2 biology between 2004 and March 2009. STUDY SELECTION Literature selected was based o...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 2014
ISSN: 0022-3042
DOI: 10.1111/jnc.12949